Editor—Deletions of the terminal region of the long arm of chromosome 11 (bands 11q23.3-11q24) are associated with a clinically recognisable phenotype, also called Jacobsen syndrome (JS).1 Reports on more proximal 11q deletions are rare. This is the second report describing a de novo interstitial deletion of the 11q22.3-q23.2 region. The first described a de novo interstitial deletion of the 11q22.3-q23.2 region in a mildly retarded male with minor dysmorphic signs (high and narrow palate, low set, dysplastic ears, small hands and feet, and slender fingers) and epileptic seizures.2 However, no FISH studies were performed in this patient.

In this report we describe a small de novo interstitial deletion in the long arm of chromosome 11 (bands q22.3-q23.2) in a 2 year 8 month old boy with mild developmental delay and without major associated dysmorphic features or a clinically recognisable phenotype.