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  • Disruption of one intra-chain disulphide bond in the carboxyl-terminal propeptide of the proα1(I) chain of type I procollagen permits slow assembly and secretion of overmodified, but stable procollagen trimers and results in mild osteogenesis imperfecta

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Original article
Disruption of one intra-chain disulphide bond in the carboxyl-terminal propeptide of the proα1(I) chain of type I procollagen permits slow assembly and secretion of overmodified, but stable procollagen trimers and results in mild osteogenesis imperfecta

Authors

  1. Dr Byers, pbyers{at}u.washington.edu
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Citation

Pace JM, Kuslich CD, Willing MC, et al
Disruption of one intra-chain disulphide bond in the carboxyl-terminal propeptide of the proα1(I) chain of type I procollagen permits slow assembly and secretion of overmodified, but stable procollagen trimers and results in mild osteogenesis imperfecta
Journal of Medical Genetics 2001;38:443-449.

Publication history

  • Revised March 27, 2001
  • Accepted March 27, 2001
  • First published July 1, 2001.
Online issue publication 
July 01, 2001

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Journal of Medical Genetics