In reference to the Letter to the Editor “Can hair be used to screen for breast cancer?” (J Med Genet2000;37:297-8), I must bring attention to a fatal flaw in the experimental data and hence the conclusions reached by Howell et al.1 If their figure is a representative example of a typical image used in their analyses, I must conclude that there is no way that this group could test our assertion that there appears to be a strong correlation between a change in the x …