Germline mutation analysis of the transforming growth factor β receptor type II (TGFBR2) and E-cadherin (CDH1) genes in early onset and familial colorectal cancer

LOVEENA VERMA; TIMOTHY R PORTER; FRANCES M RICHARDS; M HELEN RAJPAR; D GARETH R EVANS; FIONA MACDONALD; EAMONN R MAHER

doi:10.1136/jmg.38.2.e7

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Electronic letters

Germline mutation analysis of the transforming growth factor β receptor type II (TGFBR2) and E-cadherin (CDH1) genes in early onset and familial colorectal cancer

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Online download statistics by month: February 2001 to September 2024

	Abstract	Full	Pdf
Feb 2001	0	44	16
Mar 2001	0	33	16
Apr 2001	0	18	7
May 2001	0	21	0
Jun 2001	0	23	3
Jul 2001	0	23	4
Aug 2001	0	13	4
Sep 2001	0	18	0
Oct 2001	0	14	4
Nov 2001	0	8	1
Dec 2001	0	18	1
Jan 2002	0	15	1
Feb 2002	0	13	5
Mar 2002	0	15	2
Apr 2002	0	17	5
May 2002	0	11	7
Jun 2002	0	3	0
Jul 2002	0	11	2
Aug 2002	0	8	8
Sep 2002	0	7	3
Oct 2002	0	5	0
Nov 2002	0	11	4
Dec 2002	0	3	0
Jan 2003	0	4	3
Feb 2003	0	7	2
Mar 2003	0	7	4
Apr 2003	0	7	3
May 2003	0	3	1
Jun 2003	0	2	1
Jul 2003	0	66	2
Aug 2003	0	11	2
Sep 2003	0	19	4
Oct 2003	0	63	5
Nov 2003	0	12	1
Dec 2003	0	17	2
Jan 2004	0	71	6
Feb 2004	0	12	4
Mar 2004	0	25	9
Apr 2004	0	19	3
May 2004	0	44	3
Jun 2004	0	64	5
Jul 2004	0	63	7
Aug 2004	0	86	17
Sep 2004	0	79	0
Oct 2004	6	43	7
Nov 2004	7	38	0
Dec 2004	4	34	8
Jan 2005	6	32	10
Feb 2005	8	27	8
Mar 2005	4	21	8
Apr 2005	2	12	3
May 2005	0	23	4
Jun 2005	2	12	4
Jul 2005	6	14	8
Aug 2005	1	11	4
Sep 2005	1	23	16
Oct 2005	0	13	4
Nov 2005	0	13	5
Dec 2005	2	17	3
Jan 2006	4	10	2
Feb 2006	0	6	4
Mar 2006	0	13	5
Apr 2006	0	10	2
May 2006	0	9	2
Jun 2006	1	16	3
Jul 2006	0	6	3
Aug 2006	1	7	0
Sep 2006	0	7	3
Oct 2006	0	9	2
Nov 2006	0	8	5
Dec 2006	0	6	0
Jan 2007	0	8	10
Feb 2007	0	8	2
Mar 2007	1	11	7
Apr 2007	3	1	1
May 2007	1	10	2
Jun 2007	5	4	2
Jul 2007	4	10	5
Aug 2007	3	4	1
Sep 2007	2	4	5
Oct 2007	3	10	7
Nov 2007	9	18	7
Dec 2007	3	5	1
Jan 2008	5	5	4
Feb 2008	0	7	6
Mar 2008	2	3	6
Apr 2008	6	8	7
May 2008	2	8	2
Jun 2008	5	2	1
Jul 2008	0	2	0
Aug 2008	6	2	0
Sep 2008	5	13	5
Oct 2008	3	2	0
Nov 2008	8	5	4
Dec 2008	2	1	0
Jan 2009	1	3	4
Feb 2009	6	3	1
Mar 2009	7	11	5
Apr 2009	4	3	2
May 2009	2	4	1
Jun 2009	4	1	1
Jul 2009	5	0	0
Aug 2009	1	0	0
Sep 2009	4	3	1
Oct 2009	3	7	3
Nov 2009	6	7	2
Dec 2009	2	1	0
Jan 2010	2	5	5
Feb 2010	5	4	5
Mar 2010	8	2	4
Apr 2010	3	1	1
May 2010	2	7	2
Jun 2010	1	4	2
Jul 2010	2	1	1
Aug 2010	0	1	2
Sep 2010	2	2	1
Oct 2010	5	3	5
Nov 2010	5	2	5
Dec 2010	5	2	1
Jan 2011	4	1	1
Feb 2011	3	2	1
Mar 2011	2	4	1
Apr 2011	1	1	2
May 2011	5	2	1
Jun 2011	2	2	0
Jul 2011	5	0	1
Aug 2011	7	6	1
Sep 2011	4	2	1
Oct 2011	5	0	0
Nov 2011	9	1	3
Dec 2011	5	7	5
Jan 2012	7	4	3
Feb 2012	3	3	1
Mar 2012	2	2	2
Apr 2012	4	7	5
May 2012	3	3	3
Jun 2012	4	4	6
Jul 2012	3	5	2
Aug 2012	17	10	5
Sep 2012	10	5	2
Oct 2012	5	7	3
Nov 2012	0	7	0
Dec 2012	0	1	2
Jan 2013	0	13	4
Feb 2013	0	5	2
Mar 2013	0	5	2
Apr 2013	0	6	5
May 2013	0	6	2
Jun 2013	2	3	1
Jul 2013	4	8	3
Aug 2013	5	4	1
Sep 2013	6	7	4
Oct 2013	5	7	1
Nov 2013	3	7	0
Dec 2013	2	5	0
Jan 2014	2	7	2
Feb 2014	2	6	4
Mar 2014	8	13	3
Apr 2014	5	6	0
May 2014	4	14	2
Jun 2014	4	12	2
Jul 2014	3	4	0
Aug 2014	2	2	0
Sep 2014	1	4	2
Oct 2014	0	3	0
Nov 2014	0	3	0
Dec 2014	0	3	0
Jan 2015	0	5	1
Feb 2015	0	3	2
Mar 2015	2	4	0
Apr 2015	3	3	4
May 2015	7	2	2
Jun 2015	3	5	1
Jul 2015	0	1	0
Aug 2015	2	4	0
Sep 2015	1	4	3
Oct 2015	2	2	2
Nov 2015	8	4	3
Dec 2015	4	2	0
Jan 2016	3	1	1
Feb 2016	2	1	1
Mar 2016	1	3	3
Apr 2016	3	4	1
May 2016	3	3	1
Jun 2016	5	4	2
Jul 2016	7	1	1
Aug 2016	7	1	2
Sep 2016	10	3	3
Oct 2016	9	1	1
Nov 2016	6	3	1
Dec 2016	10	2	1
Jan 2017	8	1	2
Feb 2017	2	0	0
Mar 2017	2	5	1
Apr 2017	1	9	0
May 2017	0	6	0
Jun 2017	3	6	2
Jul 2017	1	1	0
Aug 2017	10	10	0
Sep 2017	7	7	0
Oct 2017	11	11	4
Nov 2017	8	8	0
Dec 2017	7	7	1
Jan 2018	17	15	1
Feb 2018	11	5	0
Mar 2018	11	9	1
Apr 2018	11	9	1
May 2018	8	6	2
Jun 2018	7	8	0
Jul 2018	8	8	1
Aug 2018	6	6	2
Sep 2018	9	9	0
Oct 2018	2	2	1
Nov 2018	7	7	0
Dec 2018	6	6	1
Jan 2019	11	7	2
Feb 2019	7	6	1
Mar 2019	9	9	5
Apr 2019	5	5	2
May 2019	12	12	2
Jun 2019	4	4	5
Jul 2019	5	5	8
Aug 2019	2	2	3
Sep 2019	7	7	2
Oct 2019	9	9	3
Nov 2019	10	6	3
Dec 2019	11	7	4
Jan 2020	19	19	4
Feb 2020	4	4	4
Mar 2020	16	16	10
Apr 2020	8	8	7
May 2020	15	13	7
Jun 2020	6	6	3
Jul 2020	8	8	1
Aug 2020	4	4	3
Sep 2020	19	19	1
Oct 2020	21	21	7
Nov 2020	21	19	4
Dec 2020	22	20	4
Jan 2021	8	8	2
Feb 2021	10	10	4
Mar 2021	10	8	4
Apr 2021	11	11	4
May 2021	6	6	1
Jun 2021	14	14	1
Jul 2021	16	16	7
Aug 2021	11	13	1
Sep 2021	15	15	11
Oct 2021	8	9	17
Nov 2021	17	13	16
Dec 2021	10	10	3
Jan 2022	11	12	1
Feb 2022	9	9	5
Mar 2022	21	21	2
Apr 2022	12	10	4
May 2022	19	20	13
Jun 2022	17	18	6
Jul 2022	11	10	1
Aug 2022	19	19	5
Sep 2022	16	15	7
Oct 2022	26	26	4
Nov 2022	10	10	5
Dec 2022	5	5	3
Jan 2023	11	9	2
Feb 2023	36	26	1
Mar 2023	11	9	2
Apr 2023	11	6	1
May 2023	18	14	8
Jun 2023	12	10	1
Jul 2023	17	14	5
Aug 2023	23	19	11
Sep 2023	9	9	3
Oct 2023	15	14	6
Nov 2023	18	14	2
Dec 2023	20	2	1
Jan 2024	22	2	2
Feb 2024	24	0	0
Mar 2024	67	7	4
Apr 2024	32	0	0
May 2024	51	3	3
Jun 2024	20	0	1
Jul 2024	60	3	2
Aug 2024	34	0	0
Sep 2024	11	2	1
Total	1736	2874	864

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