The recent considerable expansion in our understanding of human chromosome pathology in medicine has been reflected in the production of some excellent textbooks from the “how to” of the encyclopaedic AGT Cytogenetics Manual to the more discursive but invaluable second edition of “Gardner and Sutherland”. This multi-authored book, entitled, The Principles of Clinical Cytogenetics, aims to provide a comprehensive description of the basic concepts of clinical cytogenetics in a single volume.

This book is divided into four sections: “Basic Concepts and Background”, “Examining and Analysing …