A CGC&gt;CAT gene conversion-like event resulting in the R122H mutation in the cationic trypsinogen gene and its implication in the genotyping of pancreatitis

JIAN-MIN CHEN; ODILE RAGUENES; CLAUDE FEREC; PIERRE H DEPREZ; CHRISTINE VERELLEN-DUMOULIN

doi:10.1136/jmg.37.11.e36

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Electronic letters

A CGC>CAT gene conversion-like event resulting in the R122H mutation in the cationic trypsinogen gene and its implication in the genotyping of pancreatitis

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	Abstract	Full	Pdf
Nov 2000	0	29	7
Dec 2000	0	8	3
Jan 2001	0	6	5
Feb 2001	0	5	1
Mar 2001	0	27	1
Apr 2001	0	15	1
May 2001	0	7	1
Jun 2001	0	8	0
Jul 2001	0	3	0
Aug 2001	0	6	4
Sep 2001	0	3	0
Oct 2001	0	4	0
Nov 2001	0	7	1
Dec 2001	0	4	1
Jan 2002	0	6	1
Feb 2002	0	8	3
Mar 2002	0	2	6
Apr 2002	0	6	3
May 2002	0	6	3
Jun 2002	0	1	0
Jul 2002	0	5	3
Aug 2002	0	4	0
Oct 2002	0	2	0
Nov 2002	0	3	1
Dec 2002	0	6	2
Jan 2003	0	5	0
Feb 2003	0	6	0
Mar 2003	0	4	1
Apr 2003	0	2	0
May 2003	0	4	1
Jun 2003	0	5	1
Jul 2003	0	65	0
Aug 2003	0	13	1
Sep 2003	0	12	2
Oct 2003	0	48	0
Nov 2003	0	23	2
Dec 2003	0	19	3
Jan 2004	0	83	1
Feb 2004	0	10	0
Mar 2004	0	15	0
Apr 2004	0	17	1
May 2004	0	43	3
Jun 2004	0	39	3
Jul 2004	0	61	6
Aug 2004	0	53	0
Sep 2004	0	57	2
Oct 2004	10	28	1
Nov 2004	9	20	0
Dec 2004	4	18	3
Jan 2005	10	17	2
Feb 2005	4	14	1
Mar 2005	16	18	10
Apr 2005	8	12	0
May 2005	0	12	0
Jun 2005	3	3	2
Jul 2005	2	4	1
Aug 2005	2	17	7
Sep 2005	1	7	2
Oct 2005	0	8	2
Nov 2005	1	8	4
Dec 2005	1	12	3
Jan 2006	1	14	2
Feb 2006	0	11	4
Mar 2006	0	6	2
Apr 2006	0	17	6
May 2006	3	14	3
Jun 2006	3	9	2
Jul 2006	0	4	1
Aug 2006	1	7	0
Sep 2006	1	10	1
Oct 2006	0	12	6
Nov 2006	2	5	3
Dec 2006	0	6	2
Jan 2007	0	2	3
Feb 2007	1	4	1
Mar 2007	2	12	4
Apr 2007	3	2	2
May 2007	3	0	0
Jun 2007	5	6	2
Jul 2007	1	4	1
Aug 2007	2	5	2
Sep 2007	4	1	2
Oct 2007	3	1	1
Nov 2007	4	2	3
Dec 2007	0	6	2
Jan 2008	5	3	2
Feb 2008	2	1	1
Mar 2008	2	2	3
Apr 2008	1	4	3
May 2008	5	0	0
Jun 2008	5	1	1
Jul 2008	2	4	1
Aug 2008	13	3	0
Sep 2008	5	3	0
Oct 2008	5	0	1
Nov 2008	2	2	0
Dec 2008	1	1	0
Jan 2009	7	1	0
Feb 2009	6	0	0
Mar 2009	10	1	0
Apr 2009	8	2	2
May 2009	5	0	0
Jun 2009	3	1	1
Jul 2009	2	0	0
Aug 2009	3	1	0
Sep 2009	7	3	0
Oct 2009	3	1	0
Nov 2009	1	3	1
Dec 2009	2	0	0
Jan 2010	3	1	1
Feb 2010	3	3	4
Mar 2010	2	1	1
Apr 2010	1	0	0
May 2010	1	2	1
Jun 2010	0	1	4
Jul 2010	3	0	1
Aug 2010	3	2	2
Sep 2010	3	2	1
Oct 2010	13	6	1
Nov 2010	3	3	0
Dec 2010	3	2	0
Jan 2011	14	3	0
Feb 2011	12	4	0
Mar 2011	16	2	3
Apr 2011	9	2	0
May 2011	13	6	1
Jun 2011	9	3	0
Jul 2011	14	1	0
Aug 2011	17	2	1
Sep 2011	11	1	2
Oct 2011	13	1	0
Nov 2011	14	7	0
Dec 2011	4	8	2
Jan 2012	3	14	1
Feb 2012	1	15	0
Mar 2012	3	9	0
Apr 2012	5	10	1
May 2012	2	6	2
Jun 2012	4	9	0
Jul 2012	2	15	2
Aug 2012	2	12	1
Sep 2012	3	7	1
Oct 2012	9	16	8
Nov 2012	0	13	5
Dec 2012	0	11	2
Jan 2013	0	10	3
Feb 2013	0	8	5
Mar 2013	0	9	0
Apr 2013	0	6	2
May 2013	0	9	8
Jun 2013	4	2	0
Jul 2013	4	8	0
Aug 2013	4	6	0
Sep 2013	12	4	0
Oct 2013	5	8	5
Nov 2013	7	7	3
Dec 2013	3	6	3
Jan 2014	9	4	2
Feb 2014	0	5	2
Mar 2014	12	5	5
Apr 2014	6	10	5
May 2014	4	14	0
Jun 2014	9	6	1
Jul 2014	14	14	2
Aug 2014	10	5	0
Sep 2014	3	9	2
Oct 2014	13	4	1
Nov 2014	11	3	0
Dec 2014	4	4	4
Jan 2015	8	4	0
Feb 2015	5	3	3
Mar 2015	4	7	1
Apr 2015	2	6	1
May 2015	7	7	1
Jun 2015	1	5	0
Jul 2015	3	5	1
Aug 2015	2	5	0
Sep 2015	4	6	0
Oct 2015	3	0	1
Nov 2015	3	2	2
Dec 2015	10	8	0
Jan 2016	7	8	3
Feb 2016	6	8	5
Mar 2016	3	5	6
Apr 2016	4	0	2
May 2016	1	4	1
Jun 2016	1	0	0
Jul 2016	3	0	0
Aug 2016	5	5	4
Sep 2016	4	1	1
Oct 2016	5	1	2
Nov 2016	8	3	0
Dec 2016	8	7	1
Jan 2017	6	2	4
Feb 2017	0	5	0
Mar 2017	0	5	0
Apr 2017	0	11	1
May 2017	1	5	1
Jun 2017	4	4	2
Jul 2017	1	1	0
Aug 2017	4	4	3
Sep 2017	7	7	1
Oct 2017	7	7	2
Nov 2017	15	15	0
Dec 2017	5	3	0
Jan 2018	68	66	0
Feb 2018	19	11	1
Mar 2018	72	72	1
Apr 2018	8	8	4
May 2018	20	18	1
Jun 2018	19	17	0
Jul 2018	14	12	1
Aug 2018	32	32	1
Sep 2018	16	16	2
Oct 2018	34	34	3
Nov 2018	36	34	2
Dec 2018	36	36	8
Jan 2019	34	31	1
Feb 2019	25	25	1
Mar 2019	21	19	2
Apr 2019	7	7	6
May 2019	9	9	2
Jun 2019	8	8	0
Jul 2019	3	2	4
Aug 2019	1	1	2
Oct 2019	4	4	3
Nov 2019	27	26	8
Dec 2019	4	4	2
Jan 2020	5	5	2
Feb 2020	5	5	4
Mar 2020	6	6	3
Apr 2020	6	4	3
May 2020	18	12	3
Jun 2020	6	6	3
Jul 2020	6	6	2
Aug 2020	10	9	9
Sep 2020	12	9	0
Oct 2020	14	10	2
Nov 2020	14	10	5
Dec 2020	14	10	4
Jan 2021	8	7	2
Feb 2021	49	8	2
Mar 2021	16	11	1
Apr 2021	5	5	2
May 2021	8	8	1
Jun 2021	5	5	2
Jul 2021	5	5	7
Aug 2021	4	4	0
Sep 2021	11	10	7
Oct 2021	9	7	20
Nov 2021	7	7	11
Dec 2021	4	5	2
Jan 2022	8	8	6
Feb 2022	5	4	0
Mar 2022	8	8	2
Apr 2022	15	12	1
May 2022	19	19	7
Jun 2022	21	19	5
Jul 2022	8	6	2
Aug 2022	21	19	3
Sep 2022	20	20	7
Oct 2022	21	21	12
Nov 2022	9	8	1
Dec 2022	9	7	1
Jan 2023	20	12	3
Feb 2023	25	25	0
Mar 2023	5	5	0
Apr 2023	3	3	0
May 2023	5	5	5
Jun 2023	3	3	0
Jul 2023	10	8	4
Aug 2023	5	5	4
Sep 2023	3	3	12
Oct 2023	11	11	2
Nov 2023	6	6	1
Dec 2023	30	0	0
Jan 2024	20	1	0
Feb 2024	30	0	2
Mar 2024	124	4	0
Total	1952	2603	565

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