Table of contents

Original articles

• Polymorphisms in PTEN in breast cancer families (1 February, 1999)

  Bryan T Carroll, Fergus J Couch, Timothy R Rebbeck, Barbara L Weber
• A common MSH2 mutation in English and North American HNPCC families: origin, phenotypic expression, and sex specific differences in colorectal cancer (1 February, 1999)

  Nicola J Froggatt, Jane Green, Cecilia Brassett, D Gareth R Evans, D Timothy Bishop, Richard Kolodner, Eamonn R Maher
• Breast cancer incidence and familiality in Iceland during 75 years from 1921 to 1995 (1 February, 1999)

  Hrafn Tulinius, Helgi Sigvaldason, Gu∂rí∂ur Ólafsdóttir, Laufey Tryggvadóttir, Kristín Bjarnadóttir
• Age of onset in Huntington disease: sex specific influence of apolipoprotein E genotype and normal CAG repeat length (1 February, 1999)

  Patrick Kehoe, Michael Krawczak, Peter S Harper, Michael J Owen, A Lesley Jones
• Analysis of spinocerebellar ataxia type 2 gene and haplotype analysis: (CCG)_{1- 2} polymorphism and contribution to founder effect

  (1 February, 1999)

  Kazuyuki Mizushima, Mitsunori Watanabe, Ikuko Kondo, Koichi Okamoto, Masami Shizuka, Koji Abe, Masashi Aoki, Mikio Shoji
• Mutation screening of the RYR1 gene and identification of two novel mutations in Italian malignant hyperthermia families (1 February, 1999)

  Virginia Barone, Ornella Massa, Elena Intravaia, Adele Bracco, Antonella Di Martino, Vincenzo Tegazzin, Santolo Cozzolino, Vincenzo Sorrentino
• Mutation screening in British 21-hydroxylase deficiency families and development of novel microsatellite based approaches to prenatal diagnosis (1 February, 1999)

  Majlinda Lako, Simon Ramsden, R Duncan Campbell, Tom Strachan
• Variations in genetic assessment and recurrence risks quoted for childhood deafness: a survey of clinical geneticists (1 February, 1999)

  M J Parker, H Fortnum, I D Young, A C Davis
• A new lethal syndrome of exomphalos, short limbs, and macrogonadism (1 February, 1999)

  Laurence Faivre, Anne-Lise Delezoide, Françoise Narcy, Féréchté Razavi, Raymonde Bouvier, Valérie Cormier-Daire, Marie-Louise Briard, Stanislas Lyonnet, Michel Vekemans, Arnold Munnich, Martine Le Merrer
• Microdeletion 22q11 and oesophageal atresia (1 February, 1999)

  Maria Cristina Digilio, Bruno Marino, Pietro Bagolan, Aldo Giannotti, Bruno Dallapiccola