You are here

  • Home
  • Archive
  • Volume 33, Issue 6
  • Familial autosomal dominant dopa responsive Parkinson's disease in three living generations showing extreme anticipation and childhood onset.

Article Text

Article menu
Download PDFPDF
Research Article
Familial autosomal dominant dopa responsive Parkinson's disease in three living generations showing extreme anticipation and childhood onset.
  1. P J Morrison,
  2. R B Godwin-Austen,
  3. J A Raeburn
  1. Department of Clinical Genetics, City Hospital, Nottingham, UK.

    Abstract

    We describe a three generation family with Parkinson's disease showing autosomal dominant inheritance with extreme anticipation. Familial Parkinson's disease in three living generations is extremely rare, and anticipation is an unusual and interesting feature. Anticipation was shown in all generations and may have involved previous generations. Some cases of familial Parkinson's disease may therefore involve a trinucleotide repeat gene as part of the causal mechanism.

    https://doi.org/10.1136/jmg.33.6.504

    Statistics from Altmetric.com

      Request Permissions

      If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.