Article Text

Download PDFPDF
Familial cluster of ovarian small cell carcinoma: a new mendelian entity?
  1. M Longy,
  2. C Toulouse,
  3. P Mage,
  4. J Chauvergne,
  5. M Trojani
  1. Department of Oncogenetics, Institut Bergonié, Bordeaux, France.


    We report a pedigree in which three sisters had a particular type of ovarian cancer, small cell carcinoma of the hypercalcaemic type. This rare type of ovarian carcinoma is now well characterised by clinical and pathological findings and is well distinguished from other ovarian epithelial tumours and ovarian germ cell tumours. The occurrence of this rare type of cancer in several members of the same family and the existence of four other similar published observations raises the question of the genetic determination of this kind of tumour.

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.