Large pedigrees are fundamental to seeking new genes; they can be constructed on the basis of a family history but can frequently be enlarged considerably from public records. Genealogical sources in England and Wales consist of public records such as civil registration of births, marriages, and deaths, census returns, wills, and church records. Details are given as to their use and where they are to be found. In addition, examples are given of how archival material and pathology reports may be used to compile extensive pedigrees which can span 10 generations.
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