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Trisomy 18 and trisomy 21 mosaicism in a Down's syndrome patient.
  1. I M Thomas,
  2. R Sayee,
  3. L Shavanthi,
  4. H Sridevi
  1. Department of Anatomy, St John's Medical College, Bangalore, India.


    A male child with typical features of Down's syndrome and mosaicism of two trisomic cell lines, trisomy 18 (84%) and trisomy 21 (16%), is reported. Non-disjunction or anaphase lag of chromosomes 18 and 21 could be the cause.

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