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Paternal pericentric inversion of chromosome 4 as a cause of recurrent pregnancy loss.
  1. G C Wolf,
  2. J Mao,
  3. L Izquierdo,
  4. G Joffe
  1. Department of Obstetrics and Gynecology, University of New Mexico School of Medicine, Albuquerque 87131.


    A paternal pericentric inversion of chromosome 4 was ascertained through karyotype analysis of an abortus specimen proven to be 46,XX,rec(4),dup q, inv (4)(p13q28). The relationship of paternal pericentric inversion to pregnancy loss is discussed, and a recommendation for karyotype analysis of recurrent abortion specimens is made.

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