Article Text

Download PDFPDF
High CTG repeat number in nodular thyroid tissue from a myotonic dystrophy patient.
  1. C Daumerie,
  2. N Lannoy,
  3. J P Squifflet,
  4. G Verellen,
  5. C Verellen-Dumoulin
  1. Service d'Endocrinologie, Cliniques Universitaires St Luc, Brussels, Belgium.


    CTG triplet expansion was studied in lymphocytes and thyroid tissue in a patient with myotonic dystrophy (DM) and associated thyroid nodular disease. An approximately 7 fold larger amplification was found in abnormal thyroid tissue compared to lymphocytes, suggesting that anomalies in the putative DM kinase gene might contribute to thyroid dysfunction.

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.