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Neuroblastoma in a patient with Sotos' syndrome.
  1. M A Nance,
  2. J P Neglia,
  3. D Talwar,
  4. S A Berry
  1. Department of Pediatrics, University of Minnesota, Minneapolis 55455.


    Sotos' syndrome, or cerebral gigantism, is a disorder of growth regulation. Tumours have occasionally been reported in children with Sotos' syndrome, but it is uncertain whether this is a coincidence, or whether it is aetiologically related to the underlying disorder of growth. We report a 15 month old child with a paraspinal neuroblastoma and Sotos' syndrome and suggest that children with this condition may be at higher risk for developing tumours than the general population.

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