You are here

Article Text

Article menu
Download PDFPDF
Research Article
Theoretical considerations on germline mosaicism in Duchenne muscular dystrophy.
  1. T Grimm,
  2. B Müller,
  3. C R Müller,
  4. M Janka
  1. Institut für Humangenetik, Universität Würzburg, Federal Republic of Germany.

    Abstract

    A newly formulated mutation selection equilibrium for lethal X linked recessive traits such as Duchenne muscular dystrophy is presented, which allows for both male and female germline mosaicism. Estimates of the additional parameters used are given, thus allowing the incorporation of germline mosaicism into the calculation of genetic risks.

    https://doi.org/10.1136/jmg.27.11.683

    Statistics from Altmetric.com

      Request Permissions

      If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.