Table of contents

Research Article

• Cystic fibrosis: after the gene. (1 December, 1989)

  A Harris, M Borrow
• Genetic heterogeneity and mitochondrial DNA heteroplasmy in Leber's hereditary optic neuropathy. (1 December, 1989)

  I J Holt, D H Miller, A E Harding
• Genetic studies on a new deficiency gene (PI*Ztun) at the PI locus. (1 December, 1989)

  D B Whitehouse, C M Abbott, J U Lovegrove, I McIntosh, C J McMahon, G Mieli-Vergani, A P Mowat, D A Hopkinson
• Presymptomatic detection and prenatal diagnosis for myotonic dystrophy by means of linked DNA markers. (1 December, 1989)

  A M Norman, J L Floyd, A L Meredith, P S Harper
• Estimation of age dependent penetrance in facioscapulohumeral muscular dystrophy by minimising ascertainment bias. (1 December, 1989)

  P W Lunt, D A Compston, P S Harper
• A hungarian study on Werdnig-Hoffmann disease. (1 December, 1989)

  A Czeizel, J Hamula
• Childhood deaths in Down's syndrome. Survival curves and causes of death from a total population study in Queensland, Australia, 1976 to 1985. (1 December, 1989)

  J A Bell, J H Pearn, D Firman
• Dystrophy: a revised definition. (1 December, 1989)

  M Warburg, H U Møller
• Winchester's syndrome. (1 December, 1989)

  R M Winter
• Del(4)(q33----qter): another case report of a child with mild dysmorphism. (1 December, 1989)

  K A Fagan, R B Morris
• Features of Turner's and DiGeorge's syndromes in a child with an X;22 translocation. (1 December, 1989)

  M R Pinto, R P Leite, A Areias
• Discordant, non-syndromic, congenital diaphragmatic defects in sibs. (1 December, 1989)

  T I Farag, M A Issa, E S Mahfouz
• Porencephalic cyst in pycnodysostosis. (1 December, 1989)

  J Figueiredo, A Reis, R Vaz, M Leáo, C Cruz
• Unknown syndrome: abnormal facies, hypothyroidism, postaxial polydactyly, and severe retardation: a third patient. (1 December, 1989)

  D P Cavalcanti
• Unknown syndrome: microcephaly, hypoplastic nose, exophthalmos, gum hyperplasia, cleft palate, low set ears, and osteosclerosis. (1 December, 1989)

  J Raine, R M Winter, A Davey, S M Tucker
• Unknown syndrome: pachygyria, joint contractures, and facial abnormalities. (1 December, 1989)

  R M Winter, B N Harding, J Hyde
• Misdiagnosed normal fetus owing to undetected germinal mosaicism for DMD deletion. (1 December, 1989)

  C Boileau, C Junien
• Three different, non-mosaic sex chromosome abnormalities (direct cytotrophoblasts, mesenchymal core cultures, and abortus skin fibroblasts): implications for elucidating chorionic villi mosaicism. (1 December, 1989)

  L P Shulman, A T Tharapel, J L Simpson, C M Meyers, B Tucker, B Weisskopf, S Elias
• Association of 13q deletion and Hirschsprung's disease. (1 December, 1989)

  P Kiss, M Osztovics
• Dominantly inherited cleft lip and palate. (1 December, 1989)

  A De Paepe
• Are abortions more or less frequent once prenatal diagnosis is available? (1 December, 1989)

  S Bundey, E Boughton