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Abnormal chromosome complement resulting from a familial inversion of chromosome 2.
  1. S Richter,
  2. B Lockwood,
  3. D Lockwood,
  4. J Allanson
  1. Genetics Center of Southwest Biomedical Research Institute, Scottsdale, Arizona.


    It has been suggested that pericentric inversions of chromosome 2 increase the risk for spontaneous abortion but do not increase the risk for unbalanced recombinant offspring. We report our experience of a familial pericentric inversion of chromosome 2 resulting in two unbalanced recombinant offspring. Both subjects have 46,XX,rec(2),dup q,inv(2)(p25q35).

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