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Trisomy 18 syndrome with cleft foot.
  1. D Castle,
  2. R Bernstein
  1. Department of Human Genetics, School of Pathology, South African Institute for Medical Research, Johannesburg.


    Ectrodactyly of the feet has been reported only twice in association with trisomy 18 syndrome. A severe form of this anomaly, the first with published illustrative x rays, is described in a male infant with trisomy 18 syndrome. It is suggested that this may represent an extreme expression of the foot anomalies more commonly associated with this syndrome.

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