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Familial ectopic ossification.
  1. R J Gardner,
  2. K Yun,
  3. S M Craw
  1. Department of Paediatrics and Child Health, University of Otago, Dunedin, New Zealand.


    We report a family with dominantly inherited ectopic ossification. It is characterised by childhood onset of multifocal subcutaneous ossifications (primary osteoma cutis), which are of trivial clinical significance. One family member had extensive ectopic ossification involving one limb. We speculate that this may reflect somatic mutation having caused conversion to homozygosity.

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