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Prediction of consanguinity using human DNA fingerprints.
  1. R A Wells,
  2. B Wonke,
  3. S L Thein
  1. MRC Molecular Haematology Unit, John Radcliffe Hospital, Oxford.


    DNA fingerprinting was performed to verify the pedigree structure of a family under investigation for an unusual case of beta thalassaemia. A higher than expected proportion of hypervariable bands was shared by the proband and his mother, leading to suspicion that the child had been the product of a consanguineous mating. Further analysis of the mother's brother showed that he was almost certainly the proband's father.

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