Article Text
Research Article
Adult polycystic kidney disease and linked RFLPs at the alpha globin locus: a genetic study in the South Wales population.
Abstract
Thirteen South Wales kindreds with adult polycystic kidney disease have been studied for genetic linkage using the alpha globin and 3'HVR probes. A maximum lod score of 24.187 was found at a recombination fraction of 0.03. This study supports the existence of a single locus on chromosome 16 responsible for the disorder.