Article Text

Download PDFPDF
Segregation of a t(3;20) translocation through three generations resulting in unbalanced karyotypes in six persons.
  1. K B Nielsen,
  2. N Tommerup,
  3. B Jespersen,
  4. P Nygaard,
  5. L Kleif

    Abstract

    With the aid of high resolution chromosome banding, a t(3;20) translocation was discovered in a large family with six retarded members. The translocation involved very small terminal segments. The unbalanced products resulting in partial trisomy 20q and monosomy 3p were observed in the retarded subjects. Gene localisation studies of the ADA gene, with a presumed locus on the long arm of chromosome 20, were also carried out and seem to exclude this gene from the distal part of 20q (20q13.1----qter).

    Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.