Article Text

Download PDFPDF
Gene deletion in an Italian haemophilia B subject.
  1. F Bernardi,
  2. L del Senno,
  3. R Barbieri,
  4. D Buzzoni,
  5. R Gambari,
  6. G Marchetti,
  7. F Conconi,
  8. F Panicucci,
  9. M Positano,
  10. S Pitruzzello


    DNA from 20 Italian haemophilia B patients was analysed by the Southern blotting technique and hybridisation to a factor IX cDNA probe. A large deletion of factor IX gene was detected in one patient with antibodies to the infused factor; the EcoRI pattern of the other 19 subjects examined was normal.

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.