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Research Article
The estimation of recurrence risks in monogenic disorders using flanking marker loci.
  1. R M Winter

    Abstract

    A method is presented of calculating recurrence risks at a disease locus where there is information from flanking marker loci. This method uses output from the computer programme LIPED. Information from carrier detection tests and mutation at the disease locus can be taken into account in certain pedigrees.

    https://doi.org/10.1136/jmg.22.1.12

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