Article Text

Download PDFPDF
Antenatal diagnosis of Niemann-Pick disease in a twin pregnancy.
  1. P Donnai,
  2. D Donnai,
  3. R Harris,
  4. R Stephens,
  5. E Young,
  6. S Campbell


    An Ashkenazi Jewish woman had a child with Niemann-Pick disease in her first marriage. She subsequently remarried a man who was also heterozygous for the condition and conceived twins. Prenatal diagnostic tests were performed and one twin was shown to be homozygous and the other heterozygous for Niemann-Pick disease. The problems of prenatal diagnosis and counselling in twin pregnancies are discussed.

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.