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Beta-thalassaemia: increased chromosomal anomalies in lymphocyte cultures.
  1. G B Côté,
  2. S Papadakou-Lagoyanni


    Lymphocyte cultures from homozygotes for the beta-thalassaemia gene were found to contain chromosomal gaps, breaks, and rearrangements more often than those from controls. Culture time seemed to have a determinant effect on the results. The possible influence of folic acid deficiency is discussed.

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