Article Text

Download PDFPDF
Two pericentric inversions of human chromosome 11.
  1. K Simola,
  2. P Karli,
  3. A De La Chapelle

    Abstract

    A pericentric inv(11) (pl5q23) detectable by G-, Q-, and R-banding and occuring in 1 member of each of 3 generations of a family is described. In another family studied by several banding methods in search of chromosomal markers, a pericentric inv(11) (p11q11) was found. It was detectable only by C-banding, the darkly staining band being located on the short-arm side of the centromere. The reasons for defining this aberration as an inversion rather than a location variant are outlined. This inversion occurred in 9 members of 3 generations of a large family. There was no clear-cut evidence of any clinical consequences of these inversions either in heterozygotes or their offspring.

    Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.