Trisomy 21 mosaicism was identified by fluorescent quinacrine banding in a phenotypically normal mother, who gave birth to two children with trisomy 21 Down's syndrome.
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↵* This work was supported in part by US Public Health Service. Grant HD-02552 and Clinical Genetics Center Grant GM-19443. L.Y.F.H. and K.H. are Career Scientists of the Health Research Council of the City of New York (L.Y.F.H., I-761; K.H., I-513).
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