Article Text

Download PDFPDF
Prenatal evaluation in a case of familial Y chromosome long arm deletion (Yq—)
  1. M. Neil Macintyre,
  2. Ronald C. Rustad,
  3. Karen Boerger Turk**
  1. Case Western Reserve University, Cleveland, Ohio, USA


    A case is reported in which a deleted Y chromosome was found in a fetal karyotype during a prenatal diagnosis performed because of maternal age anxiety. Quinacrine fluorescence studies demonstrated the same deleted Y in the child's father. The possibility of a reciprocal translocation in the father with a genetically unbalanced condition in the fetus was a concern. Careful examination of the father's karyotype and the study of other reported cases involving deleted Y chromosomes led to the conclusion that the fetal karyotype was genetically balanced. The prediction of a normal fetal development was confirmed at the child's birth.

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.


    • Departments of Anatomy and Pediatrics.

    • Departments of Radiology, Anatomy, and Biology.

    • ** Department of Anatomy.

    • * Research supported in whole or in part by grants from the Brush Foundation and Atomic Energy Commission Contract No. W-31-109-ENG-78 (Report No. C00-78-281).