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Absence of the 9q+chromosome in Ph1 negative chronic myelogenous leukaemia
  1. Janet D. Rowley
  1. Department of Medicine of the University of Chicago, Chicago, Illinois, USA
  2. The Franklin McLean Memorial Research Institute,* Chicago, Illinois, USA


    Bone marrow chromosomes from four patients with Ph1 negative chronic myelogenous leukaemia have been examined with quinacrine fluorescence. The marrow cells of all four patients showed an apparently normal karyotype. This karyotype is different from that of the Ph1 positive variant in which a possible translocation (9q+;22q−) has been observed.

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    • * Operated by the University of Chicago for the United States Atomic Energy Commission; formerly the Argonne Cancer Research Hospital.