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Genetic Association in Myocardial Infarction: Ethnicity; ABO, Rh, Lea, Xga Blood Groups; G6PD Deficiency; and Abnormal Haemoglobins
  1. N. Saha*,
  2. C. C. S. Toh,
  3. M. B. Ghosh
  1. Department of Physiology, Faculty of Medicine, University of Singapore, Singapore 3
  2. Department of Medicine, Faculty of Medicine, University of Singapore, Singapore 3


    Four hundred and eighty-six patients with myocardial infarction of both sexes comprising 213 Chinese, 53 Malays, 199 Indians, and 21 Europeans, resident in Singapore were investigated for differences in relative incidence, and for the ABO, Rh, Lea, and Xga blood groups, G6PD deficiency, and haemoglobin types. Relative incidence of myocardial infarction was appreciably higher among Indians than Chinese and Malays in all age groups, more so in younger people. There was no significant difference in the distribution of the genetic markers between patient and control series in either Chinese, Malays, or Indians.

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    • * Present address: Department of Human Biology, The John Curtin School of Medical Research, The Australian National University, PO. Box 334, Canberra City, ACT 2601, Australia.

    • Dr M. B. Ghosh died on 25 February 1972 before this work was completed.