Background: In vitro and observational epidemiological studies suggest that vitamin D may
play a role in cancer prevention. However, the relationship between vitamin D and ovarian …

Genome-wide association studies have identified several risk associations for ovarian
carcinomas but not for mucinous ovarian carcinomas (MOCs). Our analysis of 1,644 MOC …

Background: Genome-wide association studies (GWAS) have so far reported 12 loci
associated with serous epithelial ovarian cancer (EOC) risk. We hypothesized that some of …

A locus at 19p13 is associated with breast cancer (BC) and ovarian cancer (OC) risk. Here
we analyse 438 SNPs in this region in 46,451 BC and 15,438 OC cases, 15,252 BRCA1 …

Background Observational studies have reported a positive association between body mass
index (BMI) and ovarian cancer risk. However, questions remain as to whether this …

Genome-wide association studies have reported 11 regions conferring risk of high-grade
serous epithelial ovarian cancer (HGSOC). Expression quantitative trait locus (eQTL) …

Smooth muscle (SM) is a spontaneously contractile tissue that provides physical support
and function to organs such as the uterus. Uterine smooth muscle–related neoplasia …

OBJECTIVES: MicroRNAs (miRNAs) are a class of small non-coding RNAs that negatively
regulate gene expression primarily through post-transcriptional modification. We tested the …

The molecular etiology of uterine leiomyosarcoma (ULMS) is poorly understood, which
accounts for the wide disparity in outcomes among women with this disease. We examined …

BRCA1 and BRCA2 dysfunction, frequently seen in high-grade serous ovarian carcinomas,
often results from germline mutations, somatic mutations, and promoter methylation …