Sexual orientation in Drosophila is altered by the satori mutation in the sex-determination gene fruitless that encodes a zinc finger protein with a BTB domain.

H Ito, K Fujitani, K Usui… - Proceedings of the …, 1996 - National Acad Sciences
We have isolated a new Drosophila mutant, satori (sat), the males of which do not court or
copulate with female flies. The sat mutation comaps with fruitless (fru) at 91B and does not …

Cytoplasmic destruction of p53 by the endoplasmic reticulum‐resident ubiquitin ligase 'Synoviolin'

S Yamasaki, N Yagishita, T Sasaki, M Nakazawa… - The EMBO …, 2007 - embopress.org
Synoviolin, also called HRD1, is an E3 ubiquitin ligase and is implicated in endoplasmic
reticulum‐associated degradation. In mammals, Synoviolin plays crucial roles in various …

Mutations in the Novel Membrane Protein Spinster Interfere with Programmed Cell Death and Cause Neural Degeneration in Drosophila melanogaster

Y Nakano, K Fujitani, J Kurihara, J Ragan… - … and cellular biology, 2001 - Taylor & Francis
Mutations in the spin gene are characterized by an extraordinarily strong rejection behavior
of female flies in response to male courtship. They are also accompanied by decreases in …

N‐acetyltransferase ARD1‐NAT1 regulates neuronal dendritic development

N Ohkawa, S Sugisaki, E Tokunaga, K Fujitani… - Genes to …, 2008 - Wiley Online Library
ARD1 and NAT1 constitute an N‐acetyltransferase complex where ARD1 holds the
enzymatic activity of the complex. The ARD1–NAT1 complex mediates N‐terminal …

The microtubule destabilizer stathmin mediates the development of dendritic arbors in neuronal cells

N Ohkawa, K Fujitani, E Tokunaga… - Journal of cell …, 2007 - journals.biologists.com
The regulation of microtubule dynamics is important for the appropriate arborization of
neuronal dendrites during development, which in turn is critical for the formation of functional …

[HTML][HTML] From behavior to development: genes for sexual behavior define the neuronal sexual switch in Drosophila

D Yamamoto, K Fujitani, K Usui, H Ito… - Mechanisms of …, 1998 - Elsevier
The isolation and analysis of Drosophila mutants with altered sexual orientation lead to the
identification of novel branches in the sex-determination cascade which govern the sexually …

[HTML][HTML] Estrogen protects the inner retina from apoptosis and ischemia-induced loss of Vesl-1L/Homer 1c immunoreactive synaptic connections

S Kaja, SH Yang, J Wei, K Fujitani, R Liu… - … & visual science, 2003 - jov.arvojournals.org
purpose. Protective effects of estrogen on nerve cells including retinal neurons have been
described previously. However, subcellular effects on synaptic connectivity in mild ischemia …

[PDF][PDF] A blood-borne PDGF/VEGF-like ligand initiates wound-induced epidermal cell migration in Drosophila larvae

Y Wu, AR Brock, Y Wang, K Fujitani, R Ueda, MJ Galko - Current Biology, 2009 - cell.com
Epidermal cell migration is critical for restoration of tissue structure and function after
damage [1]. However, the mechanisms by which differentiated cells neighboring the wound …

Genetic dissection of sexual orientation: behavioral, cellular, and molecular approaches in Drosophila melanogaster

D Yamamoto, H Ito, K Fujitani - Neuroscience research, 1996 - Elsevier
Insertional mutagenesis using P-element vectors yielded several independent mutations
that cause male homosexuality in Drosophila melanogaster. Subsequent analyses revealed …

LIRF, a gene induced during hippocampal long-term potentiation as an immediate-early gene, encodes a novel RING finger protein

R Matsuo, A Asada, K Fujitani, K Inokuchi - Biochemical and biophysical …, 2001 - Elsevier
We describe here an LTP-induced gene, LIRF, which encodes a novel protein with RING
finger and B30. 2 domains in its N-and C-terminal portions, respectively. Each domain is …