Many microRNAs (miRNAs) are evolutionarily conserved and have intriguing expression
patterns. Tissue and/or time-specific expressions of some miRNAs are presumably …

Background Increased frequency of pathogenic variants inGBA, the causative gene for
Gaucher disease, has been suggested to be associated with Parkinson disease (PD) …

Amyotrophic lateral sclerosis (ALS) is a devastating neurological disorder characterized by
the degeneration of motor neurons and typically results in death within 3–5 years from onset …

The terrestrial biosphere is a key player in slowing the accumulation of carbon dioxide in the
atmosphere. While quantification of carbon fluxes at global land scale is important for …

Occult macular dystrophy (OMD) is an inherited macular dystrophy characterized by
progressive loss of macular function but normal ophthalmoscopic appearance. Typical OMD …

It has been suggested that cytokines are associated with refractory Mycoplasma
pneumoniae pneumonia, and steroid administration is reported to be effective in this …

Objectives Although dramatic responses to MET inhibitors have been reported in patients
with MET exon 14 (METex14) mutant non-small cell lung cancer (NSCLC), the impact of …

We evaluated isolates obtained from children with Mycoplasma pneumoniae infection
throughout Japan during 2008–2015. The highest prevalence of macrolide-resistant M …

Background Autosomal recessive hereditary spastic paraplegias (AR-HSP) constitute a
heterogeneous group of neurodegenerative diseases involving pyramidal tracts dysfunction …

Autosomal-recessive cerebellar ataxias (ARCAs) are clinically and genetically
heterogeneous disorders associated with diverse neurological and nonneurological …