To capture the full spectrum of genetic risk for autism, we performed a two-stage analysis of
rare de novo and inherited coding variants in 42,607 autism cases, including 35,130 new …

We conducted a meta-analysis of genome-wide association studies of systolic (SBP) and
diastolic (DBP) blood pressure in 19,608 subjects of east Asian ancestry from the AGEN-BP …

Polygenic scores (PGS) summarize the genetic contribution of a person's genotype to a
disease or phenotype. They can be used to group participants into different risk categories …

High blood pressure (BP) is more prevalent and contributes to more severe manifestations
of cardiovascular disease (CVD) in African Americans than in any other United States ethnic …

Recent genetic association studies have identified 55 genetic loci associated with obesity or
body mass index (BMI). The vast majority, 51 loci, however, were identified in European …

Autism spectrum disorder (ASD) is a genetically heterogeneous condition, caused by a
combination of rare de novo and inherited variants as well as common variants in at least …

Vertebrate genomes encode thousands of non-coding RNAs including short non-coding
RNAs (such as microRNAs) and long non-coding RNAs (lncRNAs). Chicken (Gallus gallus) …

Congenital diaphragmatic hernia (CDH) is a severe birth defect that is often accompanied by
other congenital anomalies. Previous exome sequencing studies for CDH have supported a …

Background Pulmonary arterial hypertension (PAH) is a lethal vasculopathy characterized
by pathogenic remodeling of pulmonary arterioles leading to increased pulmonary …

Congenital diaphragmatic hernia (CDH) is a severe congenital anomaly that is often
accompanied by other anomalies. Although the role of genetics in the pathogenesis of CDH …