Malformations of cerebral cortical development include a wide range of developmental
disorders that are common causes of neurodevelopmental delay and epilepsy. In addition …

Importance Zika virus infection can be prenatally passed from a pregnant woman to her
fetus. There is sufficient evidence to conclude that intrauterine Zika virus infection is a cause …

Malformations of the cerebral cortex are being recognized more frequently as a cause of
epilepsy, developmental delay, neurological deficits, and mental retardation. Nonetheless, a …

A polymorphic CAG repeat was identified in the human α1A voltage-dependent calcium
channel subunit. To test the hypothesis that expansion of this CAG repeat could be the …

Long-range, directed migration is particularly dramatic in the cerebral cortex, where
postmitotic neurons generated deep in the brain migrate to form layers with distinct form and …

LISSENCEPHALY (agyria-pachygyria) is a human brain malformation manifested by a
smooth cerebral surface and abnormal neuronal migration1, 2. Identification of the gene (s) …

X-linked lissencephaly and" double cortex" are allelic human disorders mapping to Xq22. 3-
Xq23 associated with arrest of migrating cerebral cortical neurons. We identified a novel 10 …

Walker-Warburg syndrome (WWS) is an autosomal recessive developmental disorder
characterized by congenital muscular dystrophy and complex brain and eye abnormalities …

Megalencephaly-capillary malformation (MCAP) and megalencephaly-polymicrogyria-
polydactyly-hydrocephalus (MPPH) syndromes are sporadic overgrowth disorders …

Autism is a childhood neurodevelopmental disorder with a strong genetic component, yet
the identification of autism susceptibility loci remains elusive. We investigated 180 autism …