The global emergence of many severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) variants jeopardizes the protective antiviral immunity induced after infection or …

Thiamethoxam is the first commercial neonicotinoid insecticide from the thianicotinyl
subclass. It was discovered in the course of our optimisation program on neonicotinoids …

Carbonate rocks from the Middle Ediacaran period in locations all over the globe record the
largest excursion in carbon isotopic compositions in Earth history. This finding suggests a …

A SARS-CoV-2 variant carrying the Spike protein amino acid change D614G has become
the most prevalent form in the global pandemic. Dynamic tracking of variant frequencies …

The corticotropin-releasing factor (CRF) family of neuropeptides includes the mammalian
peptides CRF, urocortin, and urocortin II, as well as piscine urotensin I and frog sauvagine …

In aged rodents, impairments in learning and memory have been associated with an age-
dependent decline in forebrain of cholinergic function1, and recent evidence indicates that …

The HIV-1 Tat protein regulates transcription elongation through binding to the viral TAR
RNA stem-loop structure. We have isolated a novel 87 kDa cyclin C–related protein (cyclin …

There is an urgent need for an effective, oral, direct-acting therapeutic to block transmission
of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and prevent progression …

The Gram-negative bacterium Helicobacter pylori is a causative agent of gastritis and peptic
ulcer disease in humans. Strains producing the CagA antigen (cagA+) induce strong gastric …

Cyclic AMP regulates the expression of a number of genes through a conserved promoter
element, the CRE1. Moreover, transcrip-tional induction by cAMP requires the activation of …