Breast cancer is the most common cancer among women. Common variants at 27 loci have
been identified as associated with susceptibility to breast cancer, and these account for∼ …

Purpose To investigate systemic and ocular determinants of peripapillary retinal nerve fiber
layer thickness (pRNFLT) in the European population. Design Cross-sectional meta …

Estrogen receptor (ER)-negative tumors represent 20–30% of all breast cancers, with a
higher proportion occurring in younger women and women of African ancestry. The etiology …

Genome-wide association studies (GWAS) have identified four susceptibility loci for
epithelial ovarian cancer (EOC), with another two suggestive loci reaching near genome …

Breast cancer is the most common cancer among women. To date, 22 common breast
cancer susceptibility loci have been identified accounting for∼ 8% of the heritability of the …

Whilst previous studies have reported that higher BMI increases a woman's risk of
developing ovarian cancer, associations for the different histological subtypes have not …

Triple-negative (TN) breast cancer is an aggressive subtype of breast cancer associated
with a unique set of epidemiologic and genetic risk factors. We conducted a two-stage …

Analysis of 4,405 variants in 89,050 European subjects from 41 case-control studies
identified three independent association signals for estrogen-receptor-positive tumors at …

Genome-wide association studies (GWAS) of breast cancer defined by hormone receptor
status have revealed loci contributing to susceptibility of estrogen receptor (ER)-negative …

HNF1B is overexpressed in clear cell epithelial ovarian cancer, and we observed epigenetic
silencing in serous epithelial ovarian cancer, leading us to hypothesize that variation in this …