User profiles for "author:Simon Aylwin"
Simon AylwinKing's College London Verified email at nhs.net Cited by 7986 |
[HTML][HTML] International consensus on initial screening and follow-up of asymptomatic SDHx mutation carriers
L Amar, K Pacak, O Steichen, SA Akker… - Nature Reviews …, 2021 - nature.com
Approximately 20% of patients diagnosed with a phaeochromocytoma or paraganglioma
carry a germline mutation in one of the succinate dehydrogenase (SDHx) genes (SDHA …
carry a germline mutation in one of the succinate dehydrogenase (SDHx) genes (SDHA …
Gut hormone profiles following bariatric surgery favor an anorectic state, facilitate weight loss, and improve metabolic parameters
Objective: To study the effect of bariatric surgery on the entero-hypothalamic endocrine axis
of humans and rodents. Background: Bariatric surgery is the most effective obesity treatment …
of humans and rodents. Background: Bariatric surgery is the most effective obesity treatment …
Tumor risks and genotype–phenotype–proteotype analysis in 358 patients with germline mutations in SDHB and SDHD
CJ Ricketts, JR Forman, E Rattenberry… - Human …, 2010 - Wiley Online Library
Succinate dehydrogenase B (SDHB) and D (SDHD) subunit gene mutations predispose to
adrenal and extraadrenal pheochromocytomas, head and neck paragangliomas (HNPGL) …
adrenal and extraadrenal pheochromocytomas, head and neck paragangliomas (HNPGL) …
Germline CDKN1B/p27Kip1 Mutation in Multiple Endocrine Neoplasia
M Georgitsi, A Raitila, A Karhu… - The Journal of …, 2007 - academic.oup.com
Context: Germline mutations in the MEN1 gene predispose to multiple endocrine neoplasia
type 1 (MEN1) syndrome, but in up to 20–25% of clinical MEN1 cases, no MEN1 mutations …
type 1 (MEN1) syndrome, but in up to 20–25% of clinical MEN1 cases, no MEN1 mutations …
The efficacy of GLP‐1RAs for the management of postprandial hypoglycemia following bariatric surgery: a systematic review
DC Llewellyn, H Logan Ellis, SJB Aylwin, E Oštarijaš… - …, 2023 - Wiley Online Library
Objective Postprandial hyperinsulinemic hypoglycemia with neuroglycopenia is an
increasingly recognized complication of Roux‐en‐Y gastric bypass and gastric sleeve …
increasingly recognized complication of Roux‐en‐Y gastric bypass and gastric sleeve …
Gut hypertrophy after gastric bypass is associated with increased glucagon-like peptide 2 and intestinal crypt cell proliferation
CW le Roux, C Borg, K Wallis, RP Vincent… - Annals of …, 2010 - journals.lww.com
Objective: We aimed to determine changes in crypt cell proliferation and glucagon-like
peptide-2 (GLP-2) in rodents and man after Roux-en-Y gastric bypass (RYGB). Summary of …
peptide-2 (GLP-2) in rodents and man after Roux-en-Y gastric bypass (RYGB). Summary of …
Tumour risks and genotype–phenotype correlations associated with germline variants in succinate dehydrogenase subunit genes SDHB, SDHC and SDHD
Background Germline pathogenic variants in SDHB/SDHC/SDHD are the most frequent
causes of inherited phaeochromocytomas/paragangliomas. Insufficient information …
causes of inherited phaeochromocytomas/paragangliomas. Insufficient information …
Effectiveness of metyrapone in treating Cushing's syndrome: a retrospective multicenter study in 195 patients
Background: Cushing's syndrome (CS) is a severe condition with excess mortality and
significant morbidity necessitating control of hypercortisolemia. There are few data …
significant morbidity necessitating control of hypercortisolemia. There are few data …
The impact of obesity surgery and the paradox of control: A qualitative study
In light of the failure of psychological approaches to obesity some clinicians and patients are
turning to surgery. The present qualitative study aimed to explore patients' experiences of …
turning to surgery. The present qualitative study aimed to explore patients' experiences of …
[HTML][HTML] Pronounced response of papillary craniopharyngioma to treatment with vemurafenib, a BRAF inhibitor
SJB Aylwin, I Bodi, R Beaney - Pituitary, 2016 - Springer
The BRAF V600E mutation has recently been identified in a high percentage of papillary
craniopharyngiomas [1, 2]. The V600E mutation constitutively activates the MEKERK …
craniopharyngiomas [1, 2]. The V600E mutation constitutively activates the MEKERK …