User profiles for "author:Pieter Pretorius"

Pieter Pretorius

Consultant Neuroradiologist, Oxford University Hospitals NHS Trust
Verified email at ouh.nhs.uk
Cited by 1258

Is the role of circulating DNA as a biomarker of cancer being prematurely overrated?

M Van der Vaart, PJ Pretorius - Clinical biochemistry, 2010 - Elsevier
BACKGROUND: Circulating DNA is utilized widely as a genetic biomarker in a variety of
pathological conditions, mainly in cancerous conditions. Quantification of circulating DNA …

Central or atypical skull base osteomyelitis: diagnosis and treatment

MPA Clark, PM Pretorius, I Byren, CA Milford - Skull base, 2009 - thieme-connect.com
Objective: We report cases of central or atypical skull base osteomyelitis and review issues
related to the diagnosis and treatment. Methods: The four cases presented, which were …

Genetic Severity Score predicts clinical phenotype in NF2

D Halliday, B Emmanouil, P Pretorius… - Journal of medical …, 2017 - jmg.bmj.com
Background The clinical severity of disease in neurofibromatosis type 2 (NF2) is variable.
Patients affected with a constitutional truncating NF2 mutation have severe disease, while …

Surveillance for subsequent neoplasms of the CNS for childhood, adolescent, and young adult cancer survivors: a systematic review and recommendations from the …

DC Bowers, LC Verbruggen, LCM Kremer… - The lancet …, 2021 - thelancet.com
Exposure to cranial radiotherapy is associated with an increased risk of subsequent CNS
neoplasms among childhood, adolescent, and young adult (CAYA) cancer survivors …

Bevacizumab in neurofibromatosis type 2 (NF2) related vestibular schwannomas: a nationally coordinated approach to delivery and prospective evaluation

KA Morris, JF Golding, PR Axon, S Afridi… - Neuro-oncology …, 2016 - academic.oup.com
Background NF2 patients develop multiple nervous system tumors including bilateral
vestibular schwannomas (VS). The tumors and their surgical treatment are associated with …

Assessing the DNA methylation status of single cells with the comet assay

JF Wentzel, C Gouws, C Huysamen, E Van Dyk… - Analytical …, 2010 - Elsevier
The comet assay (single cell gel electrophoresis) is a cost-effective, sensitive, and simple
technique that is traditionally used for analyzing and quantifying DNA damage in individual …

[HTML][HTML] Early detection of cerebral microbleeds following traumatic brain injury using MRI in the hyper-acute phase

TP Lawrence, PM Pretorius, M Ezra… - Neuroscience …, 2017 - Elsevier
Background Traumatic brain injury (TBI) is a leading cause of death and disability in people
under 45. Advanced imaging techniques to identify injury and classify severity in the first few …

Introducing in-between decision points to TOC's five focusing steps

P Pretorius - International Journal of Production Research, 2014 - Taylor & Francis
This paper builds on the original five focusing steps as defined by Goldratt and Cox (1992)
as one of the constructs of the theory of constraints (TOC). The shortcomings identified are …

[HTML][HTML] Microbial aetiology of brain abscess in a UK cohort: prominent role of Streptococcus intermedius

CA Darlow, N McGlashan, R Kerr, S Oakley… - Journal of Infection, 2020 - Elsevier
Background Brain abscess is an uncommon condition, but carries high mortality. Current
treatment guidelines are based on limited data. Surveillance of clinical, radiological and …

Gradenigo's syndrome: successful conservative treatment in adult and paediatric patients

BJ Burston, PM Pretorius, JD Ramsden - The Journal of Laryngology …, 2005 - cambridge.org
A triad of retro-ocular pain, discharging ear and abducens nerve palsy, as described by
Gradenigo, has been recognized for 150 years. It has traditionally been treated with surgery …