A randomized controlled double-blind trial was undertaken in south Wales to prevent the
recurrence of neural-tube defects in women who had had one child with a neural-tube …

Autophagy is known to be a feature of cardiomyopathies and chronic ischaemia. Here we
demonstrate that autophagy is also induced by a single cycle of ischaemia/reperfusion (I/R …

(RECEIVED FORPUBLICATION APRIL 9, 1962) Few sights are more distressing than a
child with severe hydrocephalus associated with mental and physical defect. These cases …

Two series of liveborn spina-bifida cases (myelocele and meningocele) in South Wales, an
unoperated series of 290 cases born between 1956 and 1962 (with 54 survivors in 1968) …

Fifty‐nine families of children with spina bifida and their matched controls have been under
investigation since the children's births between 1964 and 1966. The quality of the marital …

Abstract In the period 1980–1987, neural tube defects were two to three times more
prevalent in populations covered by EUROCAT registries in the United Kingdom and Ireland …

METHODS For a detailed study of familial aggregation and epi-demiological characteristics,
cases ascertained for the whole period in four areas-6, 7, 8, and 9 (Rhondda, Aberdare …

The major central nervous system malformations, which include anencephaly, spina bifida
cystica, and congenital hydrocephalus, and their variants, have become one of our more …

One hundred and seventy-four women who had previously had a child with a neural-tube
defect were assessed retrospectively on the quality of their diets during the first trimester of …

A retrospective study examined the reactions to the termination of pregnancy for fetal
malformation and the follow up services that were available. Women resident in Mid …