We present the clinical and laboratory findings in an institutionalised adult patient originally
referred for autism. A high risk of colorectal cancer was predicted when an interstitial …

Methods and results Six couples at risk of transmitting an X linked disorder underwent seven
cycles of routine in vitro fertilisation treatment, and biopsy specimens of one or two cells …

Des-acyl ghrelin (DAG) is one of the three preproghrelin gene-encoded peptides. Compared
with ghrelin and obestatin, it has not received the attention it deserves. DAG has long been …

Ghrelin plays an important physiological role in modulating GH secretion, insulin secretion
and glucose metabolism. Ghrelin has direct effects on pancreatic islet function. Also, ghrelin …

The detection of genetic disease in the human embryo before implantation gives parents the
chance of starting a pregnancy knowing that the baby will be free of the inherited disorder …

Cytogenetic observations on seven cases of ataxia telangiectasia are presented. The
aberration frequency was found to be increased in all of them with a specificity for the …

Ghrelin exerts various metabolic activities, including regulation of glucose levels in humans.
To verify whether the glucose response to ghrelin reflects a modulation of an insulin …

A small pilot study has been carried out in order to assess the reliability of the detection of
hemizygosity at the elastin locus by fluorescence in situ hybridisation (FISH) analysis, as a …

We investigated the metabolic actions of ghrelin in humans by examining the effects of acute
administration of acylated ghrelin, unacylated ghrelin, and the combination in eight adult …

Metformin decreases endogenous glucose production by the liver. Few studies have
examined the effect of metformin on the insulin-signaling pathway in liver models, and none …