User profiles for "author:Florian Heitz"
 | Florian HeitzOberarzt der Kliniken Essen-Mitte Verified email at kem-med.com Cited by 8636 |
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
TERT-locus SNPs and leukocyte telomere measures are reportedly associated with risks of
multiple cancers. Using the Illumina custom genotyping array iCOGs, we analyzed∼ 480 …
multiple cancers. Using the Illumina custom genotyping array iCOGs, we analyzed∼ 480 …
[HTML][HTML] Progression-free survival and safety at 3.5 years of follow-up: results from the randomised phase 3 PRIMA/ENGOT-OV26/GOG-3012 trial of niraparib …
A González-Martín, B Pothuri, I Vergote… - European Journal of …, 2023 - Elsevier
Purpose To report updated long-term efficacy and safety from the double-blind, placebo-
controlled, phase 3 PRIMA/ENGOT-OV26/GOG-3012 study (NCT02655016). Methods …
controlled, phase 3 PRIMA/ENGOT-OV26/GOG-3012 study (NCT02655016). Methods …
GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer
PDP Pharoah, YY Tsai, SJ Ramus, CM Phelan… - Nature …, 2013 - nature.com
Genome-wide association studies (GWAS) have identified four susceptibility loci for
epithelial ovarian cancer (EOC), with another two suggestive loci reaching near genome …
epithelial ovarian cancer (EOC), with another two suggestive loci reaching near genome …
Triple-negative and HER2-overexpressing breast cancers exhibit an elevated risk and an earlier occurrence of cerebral metastases
PURPOSE: Evaluation of the influence of immunohistochemically defined breast cancer
(BC) subtypes and other risk factors on the development of cerebral metastases (CM) …
(BC) subtypes and other risk factors on the development of cerebral metastases (CM) …
Impact of a structured quality management program on surgical outcome in primary advanced ovarian cancer
OBJECTIVE: Surgical outcome in advanced ovarian cancer (AOC) is an important
prognostic factor and the only factor amendable to improvement by optimization. Therefore …
prognostic factor and the only factor amendable to improvement by optimization. Therefore …
Operability and chemotherapy responsiveness in advanced low-grade serous ovarian cancer. An analysis of the AGO Study Group metadatabase
Objective Since almost two decades standard 1st-line chemotherapy for advanced ovarian
cancer (AOC) has been a platinum/taxane combination. More recently, this general strategy …
cancer (AOC) has been a platinum/taxane combination. More recently, this general strategy …
Genome-wide meta-analyses of breast, ovarian, and prostate cancer association studies identify multiple new susceptibility loci shared by at least two cancer types
SP Kar, J Beesley, A Amin Al Olama, K Michailidou… - Cancer discovery, 2016 - AACR
Breast, ovarian, and prostate cancers are hormone-related and may have a shared genetic
basis, but this has not been investigated systematically by genome-wide association (GWA) …
basis, but this has not been investigated systematically by genome-wide association (GWA) …
[HTML][HTML] Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer
HNF1B is overexpressed in clear cell epithelial ovarian cancer, and we observed epigenetic
silencing in serous epithelial ovarian cancer, leading us to hypothesize that variation in this …
silencing in serous epithelial ovarian cancer, leading us to hypothesize that variation in this …
Pre-operative serum albumin is associated with post-operative complication rate and overall survival in patients with epithelial ovarian cancer undergoing …
B Ataseven, A du Bois, A Reinthaller, A Traut… - Gynecologic …, 2015 - Elsevier
Objective Hypoalbuminemia has been reported as a risk factor for post-operative
complications and unfavorable survival in cancer patients. We aimed to evaluate the …
complications and unfavorable survival in cancer patients. We aimed to evaluate the …
[HTML][HTML] Prevalence of deleterious germline variants in risk genes including BRCA1/2 in consecutive ovarian cancer patients (AGO-TR-1)
Background Identification of families at risk for ovarian cancer offers the opportunity to
consider prophylactic surgery thus reducing ovarian cancer mortality. So far, identification of …
consider prophylactic surgery thus reducing ovarian cancer mortality. So far, identification of …