Large-scale genotyping identifies 41 new loci associated with breast cancer risk

K Michailidou, P Hall, A Gonzalez-Neira… - Nature …, 2013 - nature.com
Breast cancer is the most common cancer among women. Common variants at 27 loci have
been identified as associated with susceptibility to breast cancer, and these account for∼ …

Protection from right-and left-sided colorectal neoplasms after colonoscopy: population-based study

H Brenner, M Hoffmeister, V Arndt… - Journal of the …, 2010 - academic.oup.com
Background Colonoscopy is used for early detection and prevention of colorectal cancer, but
evidence on the magnitude of overall protection and protection according to anatomical site …

A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer

AA Al Olama, Z Kote-Jarai, SI Berndt, DV Conti… - Nature …, 2014 - nature.com
Genome-wide association studies (GWAS) have identified 76 variants associated with
prostate cancer risk predominantly in populations of European ancestry. To identify …

Risk of progression of advanced adenomas to colorectal cancer by age and sex: estimates based on 840 149 screening colonoscopies

H Brenner, M Hoffmeister, C Stegmaier, G Brenner… - Gut, 2007 - gut.bmj.com
Objectives: To derive age and sex specific estimates of transition rates from advanced
adenomas to colorectal cancer by combining data of a nationwide screening colonoscopy …

Genome-wide association studies identify four ER negative–specific breast cancer risk loci

M Garcia-Closas, FJ Couch, S Lindstrom… - Nature …, 2013 - nature.com
Estrogen receptor (ER)-negative tumors represent 20–30% of all breast cancers, with a
higher proportion occurring in younger women and women of African ancestry. The etiology …

Quality of life in patients with colorectal cancer 1 year after diagnosis compared with the general population: a population-based study

V Arndt, H Merx, C Stegmaier, H Ziegler… - Journal of Clinical …, 2004 - ascopubs.org
Purpose Quality of life (QOL) has become an important outcome measure for patients with
cancer, but long-term results from population-based studies are rare. The objective of our …

Genome-wide association analysis identifies three new breast cancer susceptibility loci

M Ghoussaini, O Fletcher, K Michailidou, C Turnbull… - Nature …, 2012 - nature.com
Breast cancer is the most common cancer among women. To date, 22 common breast
cancer susceptibility loci have been identified accounting for∼ 8% of the heritability of the …

[HTML][HTML] Patient delay and stage of diagnosis among breast cancer patients in Germany–a population based study

V Arndt, T Stürmer, C Stegmaier, H Ziegler… - British journal of …, 2002 - nature.com
Early diagnosis is a tenet in oncology and should enable early treatment with the
expectation of improved outcome. Extent and determinants of patient delay of diagnosis in …

Quality of life over 5 years in women with breast cancer after breast-conserving therapy versus mastectomy: a population-based study

V Arndt, C Stegmaier, H Ziegler, H Brenner - Journal of cancer research …, 2008 - Springer
Purpose Breast-conserving therapy (BCT) was developed to improve quality of life (QOL) in
early stage breast cancer patients. Except for differences in body image, literature …

[PDF][PDF] Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers

JD French, M Ghoussaini, SL Edwards… - The American Journal of …, 2013 - cell.com
Analysis of 4,405 variants in 89,050 European subjects from 41 case-control studies
identified three independent association signals for estrogen-receptor-positive tumors at …