[HTML][HTML] HER2 expression in breast cancer primary tumours and corresponding metastases. Original data and literature review

J Carlsson, H Nordgren, J Sjöström, K Wester… - British journal of …, 2004 - nature.com
The aim of this study was to evaluate whether the HER2 expression in breast cancer is
retained in metastases. The HER2 expression in primary tumours and the corresponding …

Association analysis identifies 65 new breast cancer risk loci

K Michailidou, S Lindström, J Dennis, J Beesley, S Hui… - Nature, 2017 - nature.com
Breast cancer risk is influenced by rare coding variants in susceptibility genes, such as
BRCA1, and many common, mostly non-coding variants. However, much of the genetic …

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

K Michailidou, P Hall, A Gonzalez-Neira… - Nature …, 2013 - nature.com
Breast cancer is the most common cancer among women. Common variants at 27 loci have
been identified as associated with susceptibility to breast cancer, and these account for∼ …

[HTML][HTML] Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis …

FM Blows, KE Driver, MK Schmidt, A Broeks… - PLoS …, 2010 - journals.plos.org
Background Immunohistochemical markers are often used to classify breast cancer into
subtypes that are biologically distinct and behave differently. The aim of this study was to …

53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers

P Bouwman, A Aly, JM Escandell, M Pieterse… - Nature structural & …, 2010 - nature.com
Germ-line mutations in breast cancer 1, early onset (BRCA1) result in predisposition to
breast and ovarian cancer. BRCA1-mutated tumors show genomic instability, mainly as a …

[PDF][PDF] Polygenic risk scores for prediction of breast cancer and breast cancer subtypes

N Mavaddat, K Michailidou, J Dennis, M Lush… - The American Journal of …, 2019 - cell.com
Stratification of women according to their risk of breast cancer based on polygenic risk
scores (PRSs) could improve screening and prevention strategies. Our aim was to develop …

Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies

XR Yang, J Chang-Claude, EL Goode… - Journal of the …, 2011 - academic.oup.com
Background Previous studies have suggested that breast cancer risk factors are associated
with estrogen receptor (ER) and progesterone receptor (PR) expression status of the tumors …

A common coding variant in CASP8 is associated with breast cancer risk

A Cox, AM Dunning, M Garcia-Closas… - Nature …, 2007 - nature.com
Abstract The Breast Cancer Association Consortium (BCAC) has been established to
conduct combined case-control analyses with augmented statistical power to try to confirm …

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

K Michailidou, J Beesley, S Lindstrom, S Canisius… - Nature …, 2015 - nature.com
Genome-wide association studies (GWAS) and large-scale replication studies have
identified common variants in 79 loci associated with breast cancer, explaining∼ 14% of the …

Prediction of breast cancer risk based on profiling with common genetic variants

N Mavaddat, PDP Pharoah… - Journal of the …, 2015 - academic.oup.com
Background: Data for multiple common susceptibility alleles for breast cancer may be
combined to identify women at different levels of breast cancer risk. Such stratification could …