A single founder allele of the CHEK2 gene has been associated with predisposition to
breast and prostate cancer in North America and Europe. The CHEK2 protein participates in …

Purpose To estimate the risk of breast cancer in a woman who has a CHEK2 mutation
depending on her family history of breast cancer. Patients and Methods Seven thousand …

Three mutations in BRCA1 (5382insC, C61G and 4153delA) are common in Poland and
account for the majority of mutations identified to date in Polish breast and breast–ovarian …

Several moderate-and high-risk breast cancer susceptibility genes have been discovered,
but more are likely to exist. To discover new breast cancer susceptibility genes, we used 2 …

Background: Germline mutations in the Chek2 kinase gene (CHEK2) have been associated
with a range of cancer types. Recently, a large deletion of exons 9 and 10 of CHEK2 was …

Mutant alleles of several genes in the DNA repair pathway have been found to predispose
women to breast cancer. From a public health perspective, the importance of a given allele …

To investigate the contribution of a founder deletion in the CHEK2 gene to the burden of
breast cancer in Poland we studied 4,454 women with breast cancer and 5,496 population …

In this report the proportion of consecutive and familial breast cancer cases harboring the
657del5 of exon 6 of the NBS1 gene was determined to assess whether it is associated with …

This work describes the use of 3D printing technology to create individualized boluses for
patients treated with electron beam therapy for skin lesions of the eye canthi. It aimed to …

To investigate the relationship between CHEK2 mutation status and estrogen receptor (ER)
status in unselected cases of early‐onset breast cancer from Poland, we screened 4441 …