Genome-wide chromatin profiling efforts have shown that enhancers are often located at
large distances from gene promoters within the noncoding genome. Whereas enhancers …

Chromosome conformation capture (3C) technology is a powerful and increasingly popular
tool for analyzing the spatial organization of genomes. Several 3C variants have been …

The key haematopoietic regulator Myb is essential for coordinating proliferation and
differentiation. ChIP‐Sequencing and Chromosome Conformation Capture (3C) …

Facioscapulohumeral muscular dystrophy (FSHD) is characterized by sporadic de-
repression of the transcription factor DUX4 in skeletal muscle. DUX4 activates a cascade of …

Despite its importance during viral or bacterial infections, transcriptional regulation of the
interferon-β gene (Ifnb1) in activated macrophages is only partially understood. Here we …

With several therapeutic strategies for facioscapulohumeral muscular dystrophy (FSHD)
entering clinical testing, outcome measures are becoming increasingly important …

Microfluidic atomic force microscopy (AFM) cantilever probes have all the functionalities of a
standard AFM cantilever along with fluid pipetting. They have a channel inside the cantilever …

Facioscapulohumeral muscular dystrophy (FSHD) is one of the most prevalent skeletal
muscle dystrophies. Skeletal muscle pathology in individuals with FSHD is caused by …

Hematopoietic stem/progenitor cells (HSPCs) are regulated through numerous molecular
mechanisms that have not been interconnected. The transcription factor stem cell …

An intimate relationship exists between nuclear architecture and gene activity. Unraveling
the fine-scale three-dimensional structure of the genome and its impact on gene regulation …