Contemporary role of systematic prostate biopsies: indications, techniques, and implications for patient care

O Ukimura, JA Coleman, A De La Taille, M Emberton… - European urology, 2013 - Elsevier
CONTEXT: Prostate cancer (PCa) screening to detect early stage PCa has resulted in
increased identification of small-volume, low-grade PCa, many of which meet criteria for …

Castration-resistant prostate cancer: AUA guideline amendment

MS Cookson, WT Lowrance, MH Murad… - The Journal of …, 2015 - auajournals.org
Purpose: The purpose of this amendment is to incorporate relevant newly-published
literature to better provide a rational basis for the management of patients with castration …

Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

FR Schumacher, AA Al Olama, SI Berndt, S Benlloch… - Nature …, 2018 - nature.com
Genome-wide association studies (GWAS) and fine-mapping efforts to date have identified
more than 100 prostate cancer (PrCa)-susceptibility loci. We meta-analyzed genotype data …

Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array

RA Eeles, AAA Olama, S Benlloch, EJ Saunders… - Nature …, 2013 - nature.com
Prostate cancer is the most frequently diagnosed cancer in males in developed countries. To
identify common prostate cancer susceptibility alleles, we genotyped 211,155 SNPs on a …

Robot-assisted radical cystectomy versus open radical cystectomy in patients with bladder cancer (RAZOR): an open-label, randomised, phase 3, non-inferiority trial

DJ Parekh, IM Reis, EP Castle, ML Gonzalgo… - The Lancet, 2018 - thelancet.com
Background Radical cystectomy is the surgical standard for invasive bladder cancer. Robot-
assisted cystectomy has been proposed to provide similar oncological outcomes with lower …

A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer

AA Al Olama, Z Kote-Jarai, SI Berndt, DV Conti… - Nature …, 2014 - nature.com
Genome-wide association studies (GWAS) have identified 76 variants associated with
prostate cancer risk predominantly in populations of European ancestry. To identify …

Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

DV Conti, BF Darst, LC Moss, EJ Saunders, X Sheng… - Nature …, 2021 - nature.com
Prostate cancer is a highly heritable disease with large disparities in incidence rates across
ancestry populations. We conducted a multiancestry meta-analysis of prostate cancer …

Cognitive impairment in men with prostate cancer treated with androgen deprivation therapy: a systematic review and meta-analysis

M Sun, AP Cole, N Hanna, LA Mucci… - The Journal of …, 2018 - auajournals.org
Purpose: Use of androgen deprivation therapy may increase the risk of cognitive impairment
in men with prostate cancer. We performed a systematic review of the risk of overall …

EZH2 inhibition activates a dsRNA–STING–interferon stress axis that potentiates response to PD-1 checkpoint blockade in prostate cancer

KL Morel, AV Sheahan, DL Burkhart, SC Baca… - Nature cancer, 2021 - nature.com
Prostate cancers are considered to be immunologically 'cold'tumors given the very few
patients who respond to checkpoint inhibitor (CPI) therapy. Recently, enrichment of …

Prediction of erectile function following treatment for prostate cancer

M Alemozaffar, MM Regan, MR Cooperberg, JT Wei… - Jama, 2011 - jamanetwork.com
Context Sexual function is the health-related quality of life (HRQOL) domain most commonly
impaired after prostate cancer treatment; however, validated tools to enable personalized …