Signaling recognition events with fluorescent sensors and switches

AP De Silva, HQN Gunaratne, T Gunnlaugsson… - Chemical …, 1997 - ACS Publications
The crucial recognition events of chemistry, biology, and materials science occur in a much
smaller world than the one we are accustomed to. Information about these events can be …

Luminescent sensors and switches in the early 21st century

JF Callan, AP De Silva, DC Magri - Tetrahedron, 2005 - Elsevier
Chemically induced switching of luminescence remains one of the more dramatic visual
phenomena to be found in a laboratory. The past sliver of this century provides enough …

Combining luminescence, coordination and electron transfer for signalling purposes

AP De Silva, DB Fox, AJM Huxley, TS Moody - Coordination Chemistry …, 2000 - Elsevier
The evolution of research in luminescent signalling at Queen's University of Belfast is
critically reviewed in the context of related work from the literature. Photoinduced electron …

[PDF][PDF] Targets of T cell responses to SARS-CoV-2 coronavirus in humans with COVID-19 disease and unexposed individuals

A Grifoni, D Weiskopf, SI Ramirez, J Mateus, JM Dan… - Cell, 2020 - cell.com
Understanding adaptive immunity to SARS-CoV-2 is important for vaccine development,
interpreting coronavirus disease 2019 (COVID-19) pathogenesis, and calibration of …

[PDF][PDF] SARS-CoV-2 reverse genetics reveals a variable infection gradient in the respiratory tract

…, M Cameron, C Cameron, DJ Kelvin, A de Silva… - Cell, 2020 - cell.com
The mode of acquisition and causes for the variable clinical spectrum of coronavirus disease
2019 (COVID-19) remain unknown. We utilized a reverse genetics system to generate a …

Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans

…, A Frazier, AJ Markmann, L Premkumar, A de Silva… - Science, 2020 - science.org
Many unknowns exist about human immune responses to the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) virus. SARS-CoV-2–reactive CD4+ T cells have …

SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo

…, LV Tse, K Okuda, AJ Markmann, L Bartelt, A de Silva… - Science, 2020 - science.org
The spike aspartic acid–614 to glycine (D614G) substitution is prevalent in global severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strains, but its effects on viral …

The conservation status of the world's reptiles

…, F Cruz, JC Daltry, RJR Daniels, I Das, A de Silva… - Biological …, 2013 - Elsevier
Effective and targeted conservation action requires detailed information about species, their
distribution, systematics and ecology as well as the distribution of threat processes which …

The receptor-binding domain of the viral spike protein is an immunodominant and highly specific target of antibodies in SARS-CoV-2 patients

L Premkumar, B Segovia-Chumbez, R Jadi… - Science …, 2020 - science.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that first emerged in
late 2019 is responsible for a pandemic of severe respiratory illness. People infected with …

Alteplase versus heparin in acute pulmonary embolism: randomised trial assessing right-ventricular function and pulmonary perfusion

SZ Goldhaber, PC Come, RT Lee, E Braunwald… - The Lancet, 1993 - Elsevier
Data from a non-randomised study have hinted that in patients with acute pulmonary
embolism (PE), thrombolysis followed by heparin more rapidly reverses right-ventricular …