A frameshift mutation in human MC4R is associated with a dominant form of obesity

Nat Genet. 1998 Oct;20(2):113-4. doi: 10.1038/2407.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Amino Acid Sequence
  • Base Sequence
  • Female
  • Frameshift Mutation*
  • Humans
  • Leptin
  • Molecular Sequence Data
  • Obesity / blood
  • Obesity / genetics*
  • Pedigree
  • Polymorphism, Restriction Fragment Length
  • Polymorphism, Single-Stranded Conformational
  • Proteins / metabolism
  • Receptor, Melanocortin, Type 4
  • Receptors, Corticotropin / genetics*

Substances

  • Leptin
  • Proteins
  • Receptor, Melanocortin, Type 4
  • Receptors, Corticotropin